Africa's reported COVID-19 death toll surpassed 100,000 on Friday, a fraction of those reported on other continents but rising fast as a second wave of infections overwhelms hospitals.
The continent's reported deaths, at 100,354, compare favourably with North America, which has registered more than half a million, and Europe, which is approaching 900,000, a Reuters tally shows.
But deaths are rising sharply across Africa, driven by its southern region, especially economic powerhouse South Africa, which accounts for nearly half. South Africa was ravaged by a second wave caused by a more contagious variant that has jammed up casualty wards.
"The increased number (of infections) has led to many severe cases and some of the countries really found it quite difficult to cope," Richard Mihigo, coordinator of the immunisation programme at the World Health Organization's Africa office, told Reuters.
"We have seen some countries getting to their limit in terms of oxygen supply, which has got a really negative impact in terms of case management for severe cases."
Mihigo said the rise in deaths was pronounced in countries near South Africa like Zimbabwe, Mozambique and Malawi, raising the possibility that the 501Y.V2 variant identified in South Africa late last year had spread through the southern Africa region - although more genomic sequencing needs to be carried out to prove that.
International aid group Doctors Without Borders (MSF) this month called for urgent vaccine distributions in southern Africa to counter the spread of the new variant, as most African countries have lagged richer Western nations in launching mass vaccination programmes.